Synthesis and Antitumor Evaluation of Novel Alkylated Hydantoin and Thiohydantoin Derivatives

New alkylated hydantoin as well as 2-thiohydantoins were synthesized for broadening the library of compounds screened for antitumor activity. Antitumor activity of the new compounds was evaluated against breast cancer cell line (MCF-7) and demonstrated moderate to good activity.

Bibliographic Details
Published in:Russian Journal of General Chemistry, Vol. 89, No. 2 (2019), p. 357-363
Main Author: Ahmed, H.
Other Involved Persons: Ebead, A. ; Afifi, H. ; Abdel-Rahman, A.-H.
Format: electronic Article
Language:English
ISSN:1608-3350
Physical Description:Online-Ressource
DOI:10.1134/S1070363219020294
Subjects:
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