Multiscale fluid–structure interaction modelling to determine the mechanical stimulation of bone cells in a tissue engineered scaffold

Recent studies have shown that mechanical stimulation, by means of flow perfusion and mechanical compression (or stretching), enhances osteogenic differentiation of mesenchymal stem cells and bone cells within biomaterial scaffolds in vitro. However, the precise mechanisms by which such stimulation...

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Bibliographic Details
Published in:Biomechanics and Modeling in Mechanobiology, Vol. 14, No. 2 (2015), p. 231-243
Main Author: Zhao, Feihu
Other Involved Persons: Vaughan, J. ; Mcnamara, M.
Format: electronic Article
Language:English
ISSN:1617-7940
Physical Description:Online-Ressource
DOI:10.1007/s10237-014-0599-z
Subjects:
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