Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors : Focus on 4-Anilinoquinazolines

The 4-anilinoquinazolines (gefitinib, erlotinib and lapatinib) are members of a class of potent and selective inhibitors of the human epidermal growth factor receptor (HER) family of tyrosine kinases that have been developed to treat patients with tumours with defined genetic alterations of the HER...

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Bibliographic Details
Published in:Clinical Pharmacokinetics, Vol. 50, No. 6 (2011), p. 371-403
Main Author: Scheffler, Matthias
Other Involved Persons: Gion, Paola ; Doroshyenko, Oxana ; Wolf, J├╝rgen ; Fuhr, Uwe Prof. Dr med
Format: electronic Article
Language:English
ISSN:1179-1926
Physical Description:Online-Ressource
DOI:10.2165/11587020-000000000-00000
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