Loss of mitochondrial DNA under genotoxic stress conditions in the absence of the yeast DNA helicase Pif1p occurs independently of the DNA helicase Rrm3p
How the cellular amount of mitochondrial DNA (mtDNA) is regulated under normal conditions and in the presence of genotoxic stress is less understood. We demonstrate that the inefficient mtDNA replication process of mutant yeast cells lacking the PIF1 DNA helicase is partly rescued in the absence of...
|Published in:||Molecular Genetics and Genomics, Vol. 281, No. 6 (2009), p. 635-645|
|Other Involved Persons:||;|
|Item Description:||X. Cheng, Y. Qin contributed equally to this work. Communicated by A. Aguilera.|
|QR Code:||Show QR Code|