Loss of mitochondrial DNA under genotoxic stress conditions in the absence of the yeast DNA helicase Pif1p occurs independently of the DNA helicase Rrm3p

How the cellular amount of mitochondrial DNA (mtDNA) is regulated under normal conditions and in the presence of genotoxic stress is less understood. We demonstrate that the inefficient mtDNA replication process of mutant yeast cells lacking the PIF1 DNA helicase is partly rescued in the absence of...

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Bibliographic Details
Published in:Molecular Genetics and Genomics, Vol. 281, No. 6 (2009), p. 635-645
Main Author: Cheng, Xin
Other Involved Persons: Qin, Yong ; Ivessa, S.
Format: electronic Article
Item Description:X. Cheng, Y. Qin contributed equally to this work. Communicated by A. Aguilera.
Physical Description:Online-Ressource
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