The dual role model for p53 in maintaining genomic integrity

The tumour suppressor p53 is a potent mediator of cellular responses against genotoxic insults. In this review we describe the multiple functions of p53 in response to DNA damage, with an emphasis on p53's role in DNA repair. We summarize data demonstrating that p53 actively participates in var...

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Bibliographic Details
Published in:Cellular and Molecular Life Sciences, Vol. 55, No. 1 (1999), p. 12-27
Main Author: Janus, F.
Other Involved Persons: Albrechtsen, N. ; Dornreiter, I. ; Wiesmüller, L. ; Grosse, F. ; Deppert, W.
Format: electronic Article
Language:English
ISSN:1420-9071
Physical Description:Online-Ressource
DOI:10.1007/s000180050266
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