Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss

Adenosine and its receptors play a key role in bone homeostasis and regeneration. Extracellular adenosine is generated from CD39 and CD73 activity in the cell membrane, through conversion of adenosine triphosphate to adenosine monophosphate (AMP) and AMP to adenosine, respectively. Despite the relev...

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Bibliographic Details
Published in:Science advances, Vol. 5, No. 8 (2019), p. eaax1387
Main Author: Shih, Yu-Ru V
Other Involved Persons: Liu, Mengqian ; Kwon, Seong Keun ; Iida, Masayuki ; Gong, Ya ; Sangaj, Nivedita ; Varghese, Shyni
Format: electronic Article
Language:English
ISSN:2375-2548
Item Description:Date Revised 31.08.2019
published: Electronic-eCollection
Citation Status In-Data-Review
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1126/sciadv.aax1387
Subjects:
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