A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages

Arachidonate 15-lipoxygenase (ALOX15) and arachidonate 15-lipoxygenase, type B (ALOX15B) catalyze the dioxygenation of polyunsaturated fatty acids and are upregulated in human alternatively activated macrophages (AAMs) induced by Th2 cytokine interleukin-4 (IL-4) and/or interleukin-13. Known primari...

Full description

Bibliographic Details
Published in:Frontiers in immunology, Vol. 9 (2018), p. 1906
Main Author: Snodgrass, Ryan G
Other Involved Persons: Zezina, Ekaterina ; Namgaladze, Dmitry ; Gupta, Sahil ; Angioni, Carlo ; Geisslinger, Gerd ; Lütjohann, Dieter ; Brüne, Bernhard
Format: electronic Article
Language:English
ISSN:1664-3224
Item Description:Date Completed 30.09.2019
Date Revised 30.09.2019
published: Electronic-eCollection
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.3389/fimmu.2018.01906
Subjects:
QR Code: Show QR Code