Protein-ligand interfaces are polarized : discovery of a strong trend for intermolecular hydrogen bonds to favor donors on the protein side with implications for predicting and designing ligand complexes
Understanding how proteins encode ligand specificity is fascinating and similar in importance to deciphering the genetic code. For protein-ligand recognition, the combination of an almost infinite variety of interfacial shapes and patterns of chemical groups makes the problem especially challenging....
|Published in:||Journal of computer-aided molecular design, Vol. 32, No. 4 (2018), p. 511-528|
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|Item Description:||Date Revised 29.03.2019|
Citation Status In-Process
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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