Treatment of corneal endothelial disorders by DMEK and UT-DSAEK. Indications, complications, results and follow-up

Various techniques for posterior lamellar keratoplasty have been established for the clinical routine and continuously improved during the last 15 years so that an extremely rapid recovery of vision is possible due to very thin transplants. Descemet membrane endothelial keratoplasty (DMEK) is the me...

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Bibliographic Details
Published in:Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, Vol. 113, No. 3 (2016), p. 196-203
Main Author: Bachmann, B
Other Involved Persons: Schaub, F ; Cursiefen, C
Format: electronic Article
Language:German
ISSN:1433-0423
Item Description:Date Completed 17.01.2017
Date Revised 13.11.2018
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1007/s00347-016-0221-0
Subjects:
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246 3 |a Therapie von Hornhautendothelerkrankungen mittels DMEK und UT-DSAEK. Indikationen, Komplikationen, Ergebnisse und Nachsorge 
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520 |a Various techniques for posterior lamellar keratoplasty have been established for the clinical routine and continuously improved during the last 15 years so that an extremely rapid recovery of vision is possible due to very thin transplants. Descemet membrane endothelial keratoplasty (DMEK) is the method of choice for simple corneal endothelial diseases and has already been applied in complex conditions of the anterior segment. The learning curve for DMEK is comparatively long and the risk of complications in complex anterior segment pathologies is higher than in Descemet's stripping automated endothelial keratoplasty (DSAEK); however, DMEK results in better visual outcome and less graft rejections than DSAEK. The latest evolution in posterior lamellar transplant surgery is ultrathin DSAEK (UT-DSAEK), where the grafted lamella is much thinner than in conventional DSAEK. Currently available data suggest that the resulting visual acuity after UT-DSAEK is close to the visual acuity seen after DMEK; however, studies comparing the results after DMEK and UT-DSAEK are so far lacking. Whether the transplantation of these very thin DSAEK grafts also results in endothelial cell densities and graft rejection rates comparable to DMEK has to be proven 
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653 2 |a Descemet Stripping Endothelial Keratoplasty  |6 D057111  |a *methods  |6 Q000379 
653 2 |a Evidence-Based Medicine  |6 D019317 
653 2 |a Follow-Up Studies  |6 D005500 
653 2 |a Humans  |6 D006801 
653 2 |a Minimally Invasive Surgical Procedures  |6 D019060  |a *methods  |6 Q000379 
653 2 |a Tissue and Organ Harvesting  |6 D020858  |a *methods  |6 Q000379 
653 2 |a Treatment Outcome  |6 D016896 
653 2 |a Vision Disorders  |6 D014786  |a diagnosis  |6 Q000175  |a etiology  |6 Q000209  |a *prevention & control  |6 Q000517 
653 2 |a Visual Acuity  |6 D014792 
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655 7 |a Ophthalmic surgeon  |2 gnd 
655 7 |a Posterior lamellar keratoplasty  |2 gnd 
655 7 |a Transplant  |2 gnd 
655 7 |a Visual acuity  |2 gnd 
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700 1 |a Cursiefen, C 
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