Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. To identify new susceptibility loci, we performed meta-analysis on genome-wide association study (GWAS) results from eight independent studies from the United States (3,853 cases and 33,480 controls) and investigated the m...

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Bibliographic Details
Published in:Nature genetics, Vol. 48, No. 2 (2016), p. 189-94
Main Author: Bailey, Jessica N Cooke
Other Involved Persons: Loomis, Stephanie J ; Kang, Jae H ; Allingham, R Rand ; Gharahkhani, Puya ; Khor, Chiea Chuen ; Burdon, Kathryn P ; Aschard, Hugues ; Chasman, Daniel I ; Igo, Robert P Jr ; Hysi, Pirro G ; Glastonbury, Craig A ; Ashley-Koch, Allison ; Brilliant, Murray ; Brown, Andrew A ; Budenz, Donald L ; Buil, Alfonso ; Cheng, Ching-Yu ; Choi, Hyon ; Christen, William G ; Curhan, Gary ; De Vivo, Immaculata ; Fingert, John H ; Foster, Paul J ; Fuchs, Charles ; Gaasterland, Douglas ; Gaasterland, Terry ; Hewitt, Alex W ; Hu, Frank ; Hunter, David J ; Khawaja, Anthony P ; Lee, Richard K ; Li, Zheng ; Lichter, Paul R ; Mackey, David A ; McGuffin, Peter ; Mitchell, Paul ; Moroi, Sayoko E ; Perera, Shamira A ; Pepper, Keating W ; Qi, Qibin ; Realini, Tony ; Richards, Julia E ; Ridker, Paul M ; Rimm, Eric ; Ritch, Robert ; Ritchie, Marylyn ; Schuman, Joel S ; Scott, William K ; Singh, Kuldev ; Sit, Arthur J ; Song, Yeunjoo E ; Tamimi, Rulla M ; Topouzis, Fotis ; Viswanathan, Ananth C ; Verma, Shefali Setia ; Vollrath, Douglas ; Wang, Jie Jin ; Weisschuh, Nicole ; Wissinger, Bernd ; Wollstein, Gadi ; Wong, Tien Y ; Yaspan, Brian L ; Zack, Donald J ; Zhang, Kang ; Study, Epic-Norfolk Eye ; ANZRAG Consortium ; Weinreb, Robert N ; Pericak-Vance, Margaret A ; Small, Kerrin ; Hammond, Christopher J ; Aung, Tin ; Liu, Yutao ; Vithana, Eranga N ; MacGregor, Stuart ; Craig, Jamie E ; Kraft, Peter ; Howell, Gareth ; Hauser, Michael A ; Pasquale, Louis R ; Haines, Jonathan L ; Wiggs, Janey L
Format: electronic Article
Language:English
ISSN:1061-4036
Item Description:Date Completed 03.06.2016
Date Revised 13.11.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1038/ng.3482
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