Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

Glaucoma is characterized by irreversible optic nerve degeneration and is the most frequent cause of irreversible blindness worldwide. Here, the International Glaucoma Genetics Consortium conducts a meta-analysis of genome-wide association studies of vertical cup-disc ratio (VCDR), an important dise...

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Bibliographic Details
Published in:Nature communications, Vol. 5 (2014), p. 4883
Main Author: Springelkamp, Henriët
Other Involved Persons: Höhn, René ; Mishra, Aniket ; Hysi, Pirro G ; Khor, Chiea-Chuen ; Loomis, Stephanie J ; Bailey, Jessica N Cooke ; Gibson, Jane ; Thorleifsson, Gudmar ; Janssen, Sarah F ; Luo, Xiaoyan ; Ramdas, Wishal D ; Vithana, Eranga ; Nongpiur, Monisha E ; Montgomery, Grant W ; Xu, Liang ; Mountain, Jenny E ; Gharahkhani, Puya ; Lu, Yi ; Amin, Najaf ; Karssen, Lennart C ; Sim, Kar-Seng ; van Leeuwen, Elisabeth M ; Iglesias, Adriana I ; Verhoeven, Virginie J M ; Hauser, Michael A ; Loon, Seng-Chee ; Despriet, Dominiek D G ; Nag, Abhishek ; Venturini, Cristina ; Sanfilippo, Paul G ; Schillert, Arne ; Kang, Jae H ; Landers, John ; Jonasson, Fridbert ; Cree, Angela J ; van Koolwijk, Leonieke M E ; Rivadeneira, Fernando ; Souzeau, Emmanuelle ; Jonsson, Vesteinn ; Menon, Geeta ; Blue Mountains Eye Study—GWAS group ; Weinreb, Robert N ; de Jong, Paulus T V M ; Oostra, Ben A ; Uitterlinden, André G ; Hofman, Albert ; Ennis, Sarah ; Thorsteinsdottir, Unnur ; Burdon, Kathryn P ; NEIGHBORHOOD Consortium ; Wellcome Trust Case Control Consortium 2 (WTCCC2) ; Spector, Timothy D ; Mirshahi, Alireza ; Saw, Seang-Mei ; Vingerling, Johannes R ; Teo, Yik-Ying ; Haines, Jonathan L ; Wolfs, Roger C W ; Lemij, Hans G ; Tai, E-Shyong ; Jansonius, Nomdo M ; Jonas, Jost B ; Cheng, Ching-Yu ; Aung, Tin ; Viswanathan, Ananth C ; Klaver, Caroline C W ; Craig, Jamie E ; Macgregor, Stuart ; Mackey, David A ; Lotery, Andrew J ; Stefansson, Kari ; Bergen, Arthur A B ; Young, Terri L ; Wiggs, Janey L ; Pfeiffer, Norbert ; Wong, Tien-Yin ; Pasquale, Louis R ; Hewitt, Alex W ; van Duijn, Cornelia M ; Hammond, Christopher J ; Mitchell, Paul ; Wang, Jie Jin ; Rochtchina, Elena ; Attia, John ; Scott, Rodney ; Holliday, Elizabeth G ; Baird, Paul N ; Xie, Jing ; Inouye, Michael ; Viswanathan, Ananth ; Sim, Xueling ; Allingham, R Rand ; Brilliant, Murray H ; Budenz, Donald L ; Christen, William G ; Fingert, John ; Friedman, David S ; Gaasterland, Douglas ; Gaasterland, Terry ; Kang, Jae Hee ; Kraft, Peter ; Lee, Richard K ; Lichter, Paul R ; Liu, Yutao ; Moroi, Sayoko E ; Pericak-Vance, Margaret A ; Realini, Anthony ; Richards, Julia E ; Schuman, Joel S ; Scott, William K ; Singh, Kuldev ; Sit, Arthur J ; Vollrath, Douglas ; Wollstein, Gadi ; Zack, Donald J ; Zhang, Kang ; Donnelly, Peter ; Barroso, Ines ; Blackwell, Jenefer M ; Bramon, Elvira ; Brown, Matthew A ; Casas, Juan P ; Corvin, Aiden ; Deloukas, Panos ; Duncanson, Audrey ; Jankowski, Janusz ; Markus, Hugh S ; Mathew, Christopher G ; Palmer, Colin N A ; Plomin, Robert ; Rautanen, Anna ; Sawcer, Stephen J ; Trembath, Richard C ; Wood, Nicholas W ; Spencer, Chris C A ; Band, Gavin ; Bellenguez, Céline ; Freeman, Colin ; Hellenthal, Garrett ; Giannoulatou, Eleni ; Pirinen, Matti ; Pearson, Richard ; Strange, Amy ; Su, Zhan ; Vukcevic, Damjan ; Langford, Cordelia ; Hunt, Sarah E ; Edkins, Sarah ; Gwilliam, Rhian ; Blackburn, Hannah ; Bumpstead, Suzannah J ; Dronov, Serge ; Gillman, Matthew ; Gray, Emma ; Hammond, Naomi ; Jayakumar, Alagurevathi ; McCann, Owen T ; Liddle, Jennifer ; Potter, Simon C ; Ravindrarajah, Radhi ; Ricketts, Michelle ; Waller, Matthew ; Weston, Paul ; Widaa, Sara ; Whittaker, Pamela
Format: electronic Article
Language:English
ISSN:2041-1723
Item Description:Date Completed 15.12.2015
Date Revised 13.11.2018
published: Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1038/ncomms5883
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