Complexation of alkyl groups and ghrelin in a deep, water-soluble cavitand

A cavitand with ionic, but nonionizable "feet" folds around hydrophobic guests in D2O. Short alkanes and ibuprofen are included and exchange rates are slow on the NMR timescale. Normal octanoyl groups show good affinity for the cavitand and the gastric peptide ghrelin is bound at low pH an...

Full description

Bibliographic Details
Published in:Chemical communications (Cambridge, England), Vol. 50, No. 38 (2014), p. 4895-7
Main Author: Zhang, Kang-Da
Other Involved Persons: Ajami, Dariush ; Gavette, Jesse V ; Rebek, Julius Jr
Format: electronic Article
Language:English
ISSN:1364-548X
Item Description:Date Completed 14.04.2015
Date Revised 15.04.2014
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1039/c4cc01643b
Subjects:
QR Code: Show QR Code