Solute carrier transporter and drug-related nephrotoxicity : the impact of proximal tubule cell models for preclinical research

INTRODUCTION: The final excretion step of several drugs is facilitated by membrane transporters of the Solute carrier (SLC) family expressed in the proximal tubules of the kidney. Membrane transporters contribute substantially to the pharmacokinetic profile of drugs and play important roles in drug-...

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Bibliographic Details
Published in:Expert opinion on drug metabolism & toxicology, Vol. 10, No. 3 (2014), p. 395-408
Main Author: Fisel, Pascale
Other Involved Persons: Renner, Olga ; Nies, Anne T ; Schwab, Matthias ; Schaeffeler, Elke
Format: electronic Article
Language:English
ISSN:1742-5255
Item Description:Date Completed 26.01.2015
Date Revised 17.02.2014
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1517/17425255.2014.876990
Subjects:
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