Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas

Cationic Rh(II) complexes are able to catalyze the regioselective hydroamination of propargyl ureas in a 6-endo fashion. This transformation permits access to interesting substitution patterns of dihydropyrimidines which have found use as nucleotide exchange factor inhibitors

Bibliographic Details
Published in:Tetrahedron, Vol. 69, No. 27-28 (2013), p. 5744-5750
Main Author: Yang, Miao
Other Involved Persons: Odelberg, Shannon J ; Tong, Zongzhong ; Li, Dean Y ; Looper, Ryan E
Format: Article
Item Description:Date Revised 01.07.2019
published: Print
Citation Status PubMed-not-MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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Published in:
Tetrahedron, Vol. 69, No. 27-28 (2013), p. 5744-5750
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