Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration

Stargardt type 3 (STGD3) disease is a juvenile macular dystrophy caused by mutations in the ELOVL4 (Elongation of very long chain fatty acids 4) gene. Its protein product, ELOVL4, is an elongase required for the biosynthesis of very long-chain polyunsaturated fatty acids (VLC-PUFAs). It is unclear w...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 13 (2013), p. 5181-6
Main Author: Barabas, Peter
Other Involved Persons: Liu, Aihua ; Xing, Wei ; Chen, Ching-Kang ; Tong, Zongzhong ; Watt, Carl B ; Jones, Bryan W ; Bernstein, Paul S ; Križaj, David
Format: electronic Article
Language:English
ISSN:1091-6490
Item Description:Date Completed 23.05.2013
Date Revised 13.11.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1073/pnas.1214707110
Subjects:
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