On the mutational topology of the bacterial genome

By sequencing the genomes of 34 mutation accumulation lines of a mismatch-repair defective strain of Escherichia coli that had undergone a total of 12,750 generations, we identified 1625 spontaneous base-pair substitutions spread across the E. coli genome. These mutations are not distributed at rand...

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Bibliographic Details
Published in:G3 (Bethesda, Md.), Vol. 3, No. 3 (2013), p. 399-407
Main Author: Foster, Patricia L (Author)
Other Involved Persons: Hanson, Andrew J ; Lee, Heewook ; Popodi, Ellen M ; Tang, Haixu
Format: electronic Article
Item Description:Date Completed 25.09.2013
Date Revised 13.11.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
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