Stability enhancement of drug layered pellets in a fixed dose combination tablet

The purpose of this research was to develop a stable fixed dose combination tablet for a model DPP-IV inhibitor and metformin hydrochloride. The dipeptidyl peptidase IV (DPP-IV) inhibitor was particularly challenging to formulate due to its significant chemical instability and moisture sensitivity....

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Bibliographic Details
Published in:AAPS PharmSciTech, Vol. 14, No. 1 (2013), p. 312-20
Main Author: Burke, Matthew D (Author)
Other Involved Persons: He, Xiaorong ; Cook, Chris ; Petrov, Greg A ; Long, Susan ; Coffin, Mark D
Format: electronic Article
Language:English
ISSN:1530-9932
Item Description:Date Completed 12.08.2013
Date Revised 13.11.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1208/s12249-012-9911-3
Subjects:
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