High levels of gene expression explain the strong evolutionary constraint of mitochondrial protein-coding genes

The nearly neutral theory of molecular evolution has been widely accepted as the guiding principle for understanding how selection affects gene sequence evolution. One of its central predictions is that the rate at which proteins evolve should negatively scale with effective population size (N(e))....

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Bibliographic Details
Published in:Molecular biology and evolution, Vol. 30, No. 2 (2013), p. 272-84
Main Author: Nabholz, Benoit (Author)
Other Involved Persons: Ellegren, Hans ; Wolf, Jochen B W
Format: electronic Article
Item Description:Date Completed 25.06.2013
Date Revised 16.11.2017
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
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