VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation

OBJECTIVE: The pharmacokinetics of phylloquinone (vitamin K1) were evaluated in healthy human adult volunteers (15 male and 15 female) following oral and intravenous administration of a mixed micelles formulation (Konakion MM 2 mg) in an open label study design. The subjects were allocated to one of...

Full description

Bibliographic Details
Published in:European journal of clinical pharmacology, Vol. 69, No. 3 (2013), p. 467-75
Main Author: Marinova, Milka (Author)
Other Involved Persons: Lütjohann, Dieter ; Breuer, Olof ; Kölsch, Heike ; Westhofen, Philipp ; Watzka, Matthias ; Mengel, Martin ; Stoffel-Wagner, Birgit ; Hartmann, Gunther ; Coch, Christoph ; Oldenburg, Johannes
Format: electronic Article
Language:English
ISSN:1432-1041
Item Description:Date Completed 01.08.2013
Date Revised 13.11.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1007/s00228-012-1362-y
Subjects:
QR Code: Show QR Code