Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes

Targeted ablation of the novel flavoheme reductase Ncb5or knock-out (KO) results in progressive loss of pancreatic beta-cells and white adipose tissue over time. Lipoatrophy persisted in KO animals in which the confounding metabolic effects of diabetes were eliminated by islet transplantation (trans...

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Bibliographic Details
Published in:The Journal of biological chemistry, Vol. 283, No. 43 (2008), p. 29285-91
Main Author: Larade, Kevin
Other Involved Persons: Jiang, Zhigang ; Zhang, Yongzhao ; Wang, WenFang ; Bonner-Weir, Susan ; Zhu, Hao ; Bunn, H Franklin
Format: electronic Article
Language:English
ISSN:1083-351X
Item Description:Date Completed 11.12.2008
Date Revised 13.11.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description:Online-Ressource
DOI:10.1074/jbc.M804645200
Subjects:
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