A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor

A cell-sensor assay for stabilization of IkappaBalpha was developed in the activated B cell-like diffuse large B-cell lymphoma cell line OCI-Ly3. This cell line expresses known nuclear factor kappaB (NFkappaB) target genes due to high constitutive activity of IkappaB kinase (IKK), which phosphorylat...

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Bibliographic Details
Published in:Assay and drug development technologies, Vol. 5, No. 1 (2007), p. 85-103
Main Author: Davis, R Eric
Other Involved Persons: Zhang, Ya-Qin ; Southall, Noel ; Staudt, Louis M ; Austin, Christopher P ; Inglese, James ; Auld, Douglas S
Format: Article
Language:English
ISSN:1557-8127
Item Description:Date Completed 24.04.2007
Date Revised 24.11.2016
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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