Gene expression profiling of liver cells after copper overload in vivo and in vitro reveals new copper-regulated genes

Copper toxicity in the liver is mediated by free-radical generation, resulting in oxidative stress. To prevent toxic accumulation of copper, liver cells adapt to high copper levels. Here, we used microarray analysis to compare the adaptive responses on global gene expression in liver cells exposed t...

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Bibliographic Details
Published in:Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 12, No. 4 (2007), p. 495-507
Main Author: Muller, Patricia
Other Involved Persons: van Bakel, Harm ; van de Sluis, Bart ; Holstege, Frank ; Wijmenga, Cisca ; Klomp, Leo W J
Format: Article
Language:English
ISSN:1432-1327
Item Description:Date Completed 21.08.2007
Date Revised 13.11.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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