Methodological issues with adaptation of clinical trial design

Adaptation of clinical trial design generates many issues that have not been resolved for practical applications, though statistical methodology has advanced greatly. This paper focuses on some methodological issues. In one type of adaptation such as sample size re-estimation, only the postulated va...

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Bibliographic Details
Published in:Pharmaceutical statistics, Vol. 5, No. 2 (2006), p. 99-107
Main Author: Hung, H M James
Other Involved Persons: Wang, Sue-Jane ; O'Neill, Robert T
Format: Article
Item Description:Date Completed 09.07.2007
Date Revised 27.10.2019
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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