Reduced brain cholesterol content in arylsulfatase A-deficient mice

Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder caused by deficiency in arylsulfatase A (ASA). Concentrations of cholesterol and its metabolites were determined in ASA deficient [ASA(-/-)] mice which serve as an animal model of MLD. We observed a significant reduction in cholester...

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Bibliographic Details
Published in:Biochemical and biophysical research communications, Vol. 344, No. 2 (2006), p. 647-50
Main Author: Lütjohann, Dieter (Author)
Other Involved Persons: Harzer, Klaus ; Gieselmann, Volkmar ; Eckhardt, Matthias
Format: Article
Item Description:Date Completed 22.06.2006
Date Revised 21.11.2013
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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