Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8

The ATP binding cassette transporters ABCG5 (G5) and ABCG8 (G8) limit the accumulation of neutral sterols by restricting sterol uptake from the intestine and promoting sterol excretion into bile. Humans and mice lacking G5 and G8 (G5G8-/-) accumulate plant sterols in the blood and tissues. However,...

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Bibliographic Details
Published in:Journal of lipid research, Vol. 46, No. 8 (2005), p. 1739-44
Main Author: Yu, Liqing
Other Involved Persons: von Bergmann, Klaus ; Lütjohann, Dieter ; Hobbs, Helen H ; Cohen, Jonathan C
Format: Article
Item Description:Date Completed 28.11.2005
Date Revised 01.12.2018
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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