PML mediates IFN-alpha-induced apoptosis in myeloma by regulating TRAIL induction

Interferon (IFN) induces expression of proapoptotic genes and has been used in the clinical treatment of multiple myeloma. The promyelocytic leukemia (PML) gene is an IFN-induced target that encodes a tumor suppressor protein. PML protein is typically localized within discrete speckled nuclear struc...

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Bibliographic Details
Published in:Blood, Vol. 105, No. 3 (2005), p. 1280-7
Main Author: Crowder, Chun
Other Involved Persons: Dahle, Øyvind ; Davis, R Eric ; Gabrielsen, Odd S ; Rudikoff, Stuart
Format: Article
Item Description:Date Completed 21.04.2005
Date Revised 24.11.2016
published: Print-Electronic
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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Published in:
Blood, Vol. 105, No. 3 (2005), p. 1280-7
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