The expression of heat shock protein 70 in rat brain after +Gz exposure

UNLABELLED: To investigate the effect of +Gz exposure on the expression and distribution of heat shock protein 70 (HSP70) in rat brain

Bibliographic Details
Published in:Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology, Vol. 9, No. 1 (2002), p. P23-4
Main Author: Sun, Xi-Qing (Author)
Other Involved Persons: Li, Jin-Sheng ; Wu, Xing-Yu
Format: Article
Language:English
ISSN:1077-9248
Item Description:Date Completed 24.03.2015
Date Revised 03.01.2004
published: Print
Citation Status PubMed-not-MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Subjects:
QR Code: Show QR Code
LEADER 02319naa a2200373 c 4500
001 NLM144142686
003 DE-601
005 20181226164416.0
008 180203s2002 000 0 eng d
028 5 2 |a pubmed19n0481.xml 
035 |a 00030125 
035 |a (DE-599)NLM14703669 
040 |b ger  |c GBVCP 
041 0 |a eng 
100 1 |a Sun, Xi-Qing  |e verfasserin  |4 aut 
245 1 4 |a The expression of heat shock protein 70 in rat brain after +Gz exposure 
500 |a Date Completed 24.03.2015 
500 |a Date Revised 03.01.2004 
500 |a published: Print 
500 |a Citation Status PubMed-not-MEDLINE 
500 |a Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine 
520 |a UNLABELLED: To investigate the effect of +Gz exposure on the expression and distribution of heat shock protein 70 (HSP70) in rat brain 
520 |a METHODS: One hundred rats were randomly divided into control group, +2 Gz, +6 Gz and +10 Gz exposures groups. The +Gz group rats were exposed to +2 Gz, +4 Gz, +6 Gz and +10 Gz for 3 minute respectively. The expression of HSP70 in rat brain was measured by immunohistochemistry and West blot methods after +Gz exposure 
520 |a RESULTS: There was no HSP70 expression in the brains of control rats. In +2, +4. and +6 Gz groups, HSP70 was obviously expressed in cortex, hippocampus and pyriform cortex 6 h after exposures, and strongly expressed 1 d after exposure, and then had a tendency to decrease 2 d after exposure, and returned to control level 6 d after exposure. The expression of HSP70 after +6 Gz exposure was the strongest in all +Gz groups. In +10 GZ group, HSP70 protein was only weakly expressed in pyriform cortex after exposure 
520 |a CONCLUSIONS: +Gz exposures may cause time-dependent HSP70 expression in rat brain 
611 2 7 |a Research Support, Non-U.S. Gov't  |2 gnd 
689 0 0 |A f  |a Research Support, Non-U.S. Gov't 
689 0 |5 DE-601 
700 1 |a Li, Jin-Sheng  |e verfasserin  |4 aut 
700 1 |a Wu, Xing-Yu  |e verfasserin  |4 aut 
773 0 8 |i in  |t Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology  |g Vol. 9, No. 1 (2002), p. P23-4  |q 9:1<P23-4  |w (DE-601)NLM093813813  |x 1077-9248 
912 |a GBV_NLM 
951 |a AR 
952 |d 9  |j 2002  |e 1  |c 07  |h P23-4