Total synthesis and conformational analysis of the antifungal agent (-)-PF1163B

[reaction: see text]. (-)-PF1163B, a new macrocyclic antifungal antibiotic isolated from Streptomyces sp., has been prepared in eight steps from (S)-citronellene. The key step is a ring-closing metathesis reaction of an ester and amide derivative obtained from a substituted N-methyl-l-tyrosine

Bibliographic Details
Published in:Organic letters, Vol. 5, No. 22 (2003), p. 4049-52
Main Author: Bouazza, Fodil
Other Involved Persons: Renoux, Brigitte ; Bachmann, Christian ; Gesson, Jean-Pierre
Format: Article
Item Description:Date Completed 23.06.2004
Date Revised 19.11.2009
published: Print
ErratumIn: Org Lett. 2004 Mar 18;6(6):1069
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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