Characterization of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene

To determine whether the CYP2E1 genetic polymorphisms cause alterations in protein expression and enzyme catalytic activities, three CYP2E1 genetic polymorphisms, namely RsaI/PstI, DraI, and MspI types, were determined in liver genomic DNA isolated from 39 Japanese and 45 Caucasians. These genotypes...

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Bibliographic Details
Published in:Archives of toxicology, Vol. 74, No. 7 (2000), p. 372-8
Main Author: Inoue, K
Other Involved Persons: Yamazaki, H ; Shimada, T
Format: Article
Item Description:Date Completed 18.01.2001
Date Revised 06.09.2019
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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