CYP2A6 genetic polymorphisms and liver microsomal coumarin and nicotine oxidation activities in Japanese and Caucasians

Genotypes of CYP2A6, namely CYP2A6(*)1 (wild-type), CYP2A6(*)2, and CYP2A6(*)3, were examined in liver DNA of 39 Japanese and 43 Caucasians using two-step polymerase chain reaction (PCR) methods. We first amplified a DNA fragment (1725 bp) located between near middle of exon 1 and end of exon 4 of t...

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Bibliographic Details
Published in:Archives of toxicology, Vol. 73, No. 10-11 (2000), p. 532-9
Main Author: Inoue, K
Other Involved Persons: Yamazaki, H ; Shimada, T
Format: Article
Language:English
ISSN:1432-0738
Item Description:Date Completed 02.03.2000
Date Revised 05.09.2019
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Subjects:
DNA
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