Two-stage tests for studying monotherapy and combination therapy in two-by-two factorial trials

Two-stage testing involves a preliminary test of a nuisance parameter prior to testing a main hypothesis. In a two-by-two factorial trial, the treatment interaction is the nuisance to the inference about the efficacy of one of the treatments given alone. In comparing a combination therapy to both of...

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Bibliographic Details
Published in:Statistics in medicine, Vol. 12, No. 7 (1993), p. 645-60
Main Author: Hung, H M
Format: Article
Language:English
ISSN:1097-0258
Item Description:Date Completed 12.07.1993
Date Revised 30.08.2019
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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