Search for the biochemical parameters of tumor cell sensitivity and resistance to antimetabolites

The metabolism of murine tumors sensitive and resistant to 6-theopurines and 5-fluorouracil (5-FU) was studied. A positive correlation between the tumor sensitivity to thiopurines, the level of hypoxanthine-guanine-phosphoribosyl transferase and the rates of the antimetabolite incorporation into RNA...

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Bibliographic Details
Published in:Antibiotics and chemotherapy, Vol. 28 (1980), p. 48-52
Main Author: Belousova, A K
Other Involved Persons: Gerasimova, G K
Format: Article
Item Description:Date Completed 20.11.1980
Date Revised 31.10.2019
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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