Reactive oligonucleotide derivatives containing methylphosphonate groups. V. Increased effectiveness of complementary addressed modification of target DNA by alkylating derivatives of methylphosphonate analogs of octathymidylate containing N-(2-hydroxyethyl)phenazinium residues

Efficiency of the intracomplex alkylation of octadecadeoxyribonucleotide d(pC5A8C5) (target) by Rp- and Sp-individual diastereomers of the methylphosphonate octathymidylate 4-(N-methyl-N-2-chloroethylamino)benzyl phosphoramide (-pNHCH2RCl) derivatives bearing an additional N-(2-hydroxyethyl)phenazin...

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Bibliographic Details
Published in:Bioorganicheskaia khimiia, Vol. 16, No. 3 (1990), p. 370-8
Main Author: Amirkhanov, N V
Other Involved Persons: Zarytova, V F
Format: Article
Language:Russian
ISSN:0132-3423
Item Description:Date Completed 25.07.1990
Date Revised 21.11.2008
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Subjects:
DNA
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