The distribution of Msp I-induced breaks in human lymphocyte chromosomes and its relationship to common fragile sites

The restriction endonuclease MspI (cleavage site C/CGG) induces chromosomal breaks in human lymphocytes. The breakpoints are distributed non-randomly along the chromosomes and the pattern of Msp I-induced breakage depends on the recovery time (20 h or 6 h). Chromosomal bands preferentially involved...

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Bibliographic Details
Published in:Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 213, No. 2 (1989), p. 117-124
Other Involved Persons: Porfirio, B. ; Tedeschi, B. ; Vernole, P. ; Caporossi, D. ; Nicoletti, B.
Format: electronic Article
Language:English
ISSN:0027-5107
Item Description:Copyright: Copyright (c) 2002 Elsevier Science B.V.
Physical Description:Online-Ressource
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