Steric effects in the transition state of transannular cyclization reactions

Molecular mechanics calculations carried out on normal and 19-nor-5,10-secosteroidal cyclodecenone systems, in order to explain regiochemistry and ster transannular cyclization reactions of these molecules, suggest a good correlation with energies of model transition states.

Bibliographic Details
Published in:Tetrahedron, Vol. 46, No. 10 (1990), p. 3659-3666
Other Involved Persons: Dosen-Micovic, L. ; Lorenc, L. ; Mihailovic, M.L.
Format: electronic Article
Language:English
ISSN:0040-4020
Item Description:Copyright: Copyright (c) 2002 Elsevier Science Ltd
Physical Description:Online-Ressource
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