Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration

Stargardt type 3 (STGD3) disease is a juvenile macular dystrophy caused by mutations in the ELOVL4 (Elongation of very long chain fatty acids 4) gene. Its protein product, ELOVL4, is an elongase required for the biosynthesis of very long-chain polyunsaturated fatty acids (VLC-PUFAs). It is unclear w...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 13 (2013), p. 5181-5186
Main Author: Barabas, Peter
Other Involved Persons: Liu, Aihua ; Xing, Wei ; Chen, Ching-Kang ; Tong, Zongzhong ; Watt, Carl B. ; Jones, Bryan W. ; Bernstein, Paul S. ; Križaj, David
Format: electronic Article
Language:English
ISSN:1091-6490
Item Description:Copyright: copyright © 1993-2008 National Academy of Sciences of the United States of America
Physical Description:Online-Ressource
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