Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration
Stargardt type 3 (STGD3) disease is a juvenile macular dystrophy caused by mutations in the ELOVL4 (Elongation of very long chain fatty acids 4) gene. Its protein product, ELOVL4, is an elongase required for the biosynthesis of very long-chain polyunsaturated fatty acids (VLC-PUFAs). It is unclear w...
|Published in:||Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 13 (2013), p. 5181-5186|
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Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 13 (2013), p. 5181-5186