Adaptive Reversion of a Frameshift Mutation in Escherichia coli by Simple Base Deletions in Homopolymeric Runs

Spontaneous mutations are thought to occur primarily in growing cells. However, spontaneous mutations also arise in nutritionally deprived cells, and in some cases this process appears to be adaptive. Here it is reported that when a Lac$^-$ strain of Escherichia coli is under selection for lactose u...

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Bibliographic Details
Published in:Science, Vol. 265, No. 5170 (1994), p. 407-409
Main Author: Foster, Patricia L.
Other Involved Persons: Trimarchi, Jeffrey M.
Format: electronic Article
Item Description:Copyright: Copyright 1994 American Association for the Advancement of Science
Physical Description:Online-Ressource
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