Absence of a Reductase, NCB50R, Causes Insulin-Deficient Diabetes

NCB5OR is a highly conserved NAD(P)H reductase that contains a cytochrome b5-like domain at the N terminus and a cytochrome b5 reductase-like domain at the C terminus. The enzyme is located in the endoplasmic reticulum (ER) and is widely expressed in organs and tissues. Targeted inactivation of this...

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Published in:Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 29 (2004), p. 10750-10755
Main Author: Xie, Jianxin
Other Involved Persons: Zhu, Hao ; Larade, Kevin ; Ladoux, Annie ; Seguritan, Ayden ; Chu, Michelle ; Ito, Susumu ; Bronson, Roderick T. ; Leiter, Edward H. ; Zhang, Chen-Yu ; Rosen, Evan D. ; Bunn, H. Franklin ; Steiner, Donald F.
Format: electronic Article
Item Description:Copyright: Copyright 1993/2004 The National Academy of Sciences of the United States of America
Physical Description:Online-Ressource
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