Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly. Wet AMD includes typical choroidal neovascularization (CNV) and polypoidal choroidal vasculopathy (PCV). The etiology and pathogenesis of CNV and PCV are not well understood. Genome-wide association...
|Published in:||Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 35 (2011), p. 14578-14583|
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Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 35 (2011), p. 14578-14583