Isolation of Mammalian Cell Mutants Deficient in Glucose-6-phosphate Dehydrogenase Activity: Linkage to Hypoxanthine Phosphoribosyl Transferase

Mutants of Chinese hamster ovary cells deficient in glucose-6-phosphate dehydrogenase (D-glucose 6-phosphate: NADP 1-oxidoreductase, EC 1.1.1.49) activity were isolated after mutagenesis with ethyl methane sulfonate. The mutants were induced at frequencies of about 10-4and do not differ in growth pr...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences of the United States of America, Vol. 72, No. 2 (1975), p. 493-497
Main Author: Rosenstraus, Maurice
Other Involved Persons: Chasin, Lawrence A.
Format: electronic Article
Language:English
ISSN:1091-6490
Physical Description:Online-Ressource
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