Alignment-Free Genome Comparison with Feature Frequency Profiles (FFP) and Optimal Resolutions

For comparison of whole-genome (genic + nongenic) sequences, multiple sequence alignment of a few selected genes is not appropriate. One approach is to use an alignment-free method in which feature (or/-mer) frequency profiles (FFP) of whole genomes are used for comparison--a variation of a text or...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 8 (2009), p. 2677-2682
Main Author: Sims, Gregory E.
Other Involved Persons: Jun, Se-Ran ; Wu, Guohong A. ; Kim, Sung-Hou
Format: electronic Article
Language:English
ISSN:0027-8424
Physical Description:Online-Ressource
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