High-Resolution Mapping of DNA Hypermethylation and Hypomethylation in Lung Cancer

Changes in DNA methylation patterns are an important characteristic of human cancer. Tumors have reduced levels of genomic DNA methylation and contain hypermethylated CpG islands, but the full extent and sequence context of DNA hypomethylation and hypermethylation is unknown. Here, we used methylate...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 1 (2008), p. 252-257
Main Author: Rauch, Tibor A.
Other Involved Persons: Zhong, Xueyan ; Wu, Xiwei ; Wang, Melody ; Kernstine, Kemp H. ; Wang, Zunde ; Riggs, Arthur D. ; Pfeifer, Gerd P.
Format: electronic Article
Language:English
ISSN:1091-6490
Item Description:Copyright: Copyright 2008 The National Academy of Sciences of the United States of America
Physical Description:Online-Ressource
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