Association of FXR gene variants with cholelithiasis

Impairment of bile acid homeostasis is the most important risk factor of gallstone disease. Thereby the bile acid sensor farnesoid X receptor (FXR) plays a pivotal role in hepatic and intestinal bile acid metabolism. In this explorative study, the FXR gene was investigated to identify gene variants,...

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Bibliographic Details
Published in:Clinics and research in hepatology and gastroenterology, Vol. 39, No. 1 (2015), p. 68-79
Main Author: Hirobe-Jahn, Satoko
Other Involved Persons: Harsch, Simone ; Renner, Olga ; Richter, Dominique ; Müller, Oliver ; Stange, Eduard F.
Format: electronic Article
Physical Description:Online-Ressource
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