CuI-catalyzed intramolecular cyclization of 3-(2-aminophenyl)-2-bromoacrylate: synthesis of 2-carboxyindoles

Abstract A new approach was described for the synthesis of substituted 2-carboxyindole using 3-(2-aminophenyl)-2-bromo-acrylates through a CuI-catalyzed intramolecular coupling. The reactions were mild, rapid and with good to excellent yields.

Bibliographic Details
Published in:Tetrahedron letters, Vol. 55, No. 13 (2014), p. 2056-2060
Main Author: Xiao, Xiong
Other Involved Persons: Chen, Tian-Qi ; Ren, Jiangmeng ; Chen, Wei-Dong ; Zeng, Bu-Bing
Format: electronic Article
Language:English
ISSN:1873-3581
Physical Description:Online-Ressource
DOI:10.1016/j.tetlet.2013.10.048
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