Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro

Despite intensive research the physiological role and molecular mechanisms of action of the lipophilic antioxidant α-tocopherol (α-TOH) are still poorly understood. Hepatic α-TOH catabolism results in intermediate formation of the long-chain metabolites (α-LCMs) α-13′-hydroxy- and α-13′-carboxychrom...

Full description

Bibliographic Details
Published in:Free radical biology and medicine : the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research, Vol. 68 (2014), p. 43-51
Main Author: Wallert, Maria
Other Involved Persons: Mosig, Sandy ; Rennert, Knut ; Funke, Harald ; Ristow, Michael ; Pellegrino, Roberto Maria ; Cruciani, Gabriele ; Galli, Francesco ; Lorkowski, Stefan ; Birringer, Marc
Format: electronic Article
Language:English
ISSN:1873-4596
Physical Description:Online-Ressource
DOI:10.1016/j.freeradbiomed.2013.11.009
Other Editions:Show all 2 Editions
QR Code: Show QR Code