XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells

To further understand the role of XIAP in acute myeloid leukemia (AML), we suppressed XIAP expression by antisense oligonucleotides and determined the effect on gene expression profiles and biological pathways. XIAP inhibition upregulated expression of proteasome genes in a manner similar to the pro...

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Bibliographic Details
Published in:Leukemia research : clinical and laboratory studies, Vol. 37, No. 8 (2013), p. 974-979
Main Author: Carter, Bing Z.
Other Involved Persons: Mak, Duncan H. ; Wang, Zhiqiang ; Ma, Wencai ; Mak, Po Yee ; Andreeff, Michael ; Davis, R. Eric
Format: electronic Article
Physical Description:Online-Ressource
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