XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells
To further understand the role of XIAP in acute myeloid leukemia (AML), we suppressed XIAP expression by antisense oligonucleotides and determined the effect on gene expression profiles and biological pathways. XIAP inhibition upregulated expression of proteasome genes in a manner similar to the pro...
|Published in:||Leukemia research : clinical and laboratory studies, Vol. 37, No. 8 (2013), p. 974-979|
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