XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells

To further understand the role of XIAP in acute myeloid leukemia (AML), we suppressed XIAP expression by antisense oligonucleotides and determined the effect on gene expression profiles and biological pathways. XIAP inhibition upregulated expression of proteasome genes in a manner similar to the pro...

Full description

Bibliographic Details
Published in:Leukemia research : clinical and laboratory studies, Vol. 37, No. 8 (2013), p. 974-979
Main Author: Carter, Bing Z.
Other Involved Persons: Mak, Duncan H. ; Wang, Zhiqiang ; Ma, Wencai ; Mak, Po Yee ; Andreeff, Michael ; Davis, R. Eric
Format: electronic Article
Language:English
ISSN:1873-5835
Physical Description:Online-Ressource
DOI:10.1016/j.leukres.2013.04.018
QR Code: Show QR Code