Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6

The mechanism by which acetaminophen (APAP) causes liver damage evokes many aspects drug metabolism, oxidative chemistry, and genetic-predisposition. In this study, we leverage the relative resistance of female C57BL/6 mice to APAP-induced liver damage (AILD) compared to male C57BL/6 mice in order t...

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Bibliographische Detailangaben
Veröffentlicht in:Redox Biology, (01.01.2014)
1. Verfasser: Isaac Mohar (VerfasserIn)
Weitere beteiligte Personen: Brendan D. Stamper ; Peter M. Rademacher ; Collin C. White ; Sidney D. Nelson ; Terrance J. Kavanagh
Format: elektronischer Aufsatz
Sprache:English
ISSN:2213-2317
Umfang:Online-Ressource
DOI:10.1016/j.redox.2014.01.008
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