Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6

The mechanism by which acetaminophen (APAP) causes liver damage evokes many aspects drug metabolism, oxidative chemistry, and genetic-predisposition. In this study, we leverage the relative resistance of female C57BL/6 mice to APAP-induced liver damage (AILD) compared to male C57BL/6 mice in order t...

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Bibliographic Details
Published in:Redox Biology, (01.01.2014)
Main Author: Isaac Mohar (Author)
Other Involved Persons: Brendan D. Stamper ; Peter M. Rademacher ; Collin C. White ; Sidney D. Nelson ; Terrance J. Kavanagh
Format: electronic Article
Language:English
ISSN:2213-2317
Physical Description:Online-Ressource
DOI:10.1016/j.redox.2014.01.008
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