Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6
The mechanism by which acetaminophen (APAP) causes liver damage evokes many aspects drug metabolism, oxidative chemistry, and genetic-predisposition. In this study, we leverage the relative resistance of female C57BL/6 mice to APAP-induced liver damage (AILD) compared to male C57BL/6 mice in order t...
|Published in:||Redox Biology, (01.01.2014)|
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