Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors
Lynch syndrome (Hereditary non-polyposis colorectal cancer/HNPCC) is a cancer susceptibility syndrome which is caused by germline mutations in DNA mismatch repair (MMR) genes, in particular MLH1 and MSH2. A pathogenic germline mutation in the respective MMR gene is suggested by the finding of a loss...
|Published in:||Familial cancer, 11(2012), 1, Seite 19-26|
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|Item Description:||Published online: 16 November 2011|
The Dutch Cancer Genetics Group is represented by: Dr. A. Wagner, Dr. R. Sijmons, Dr. C. Aalfs, Dr. I. Kluijt, Dr. N. Hoogerbrugge, Dr. E. Gomez Garcia, Dr. F. Menko, Dr. T. Letteboer and Dr. F. Hes
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